在落幕的 ACS Spring 2025 (美國化學會春季年會) 上，多個創(chuàng)新藥物首次披露，涵蓋了腫瘤、心血管、神經系統(tǒng)疾病等多個領域。

這些小分子藥物代表了當下最前沿的藥物化學設計趨勢。這些首次亮相的“新星”是否有望成為下一代重磅新藥？跟隨小 M 一起來看看它們的背景信息。

 
Section
小結

這 12 個首次亮相的小分子藥物，不僅展示了目前藥物研發(fā)的多樣化方向 (從傳統(tǒng)抑制劑到蛋白降解劑、共價靶向劑、大環(huán)肽等)，也反映出精準醫(yī)療背景下對突變蛋白、腫瘤微環(huán)境、腦部靶點等復雜機制的深入探索。部分分子已經進入臨床階段，值得持續(xù)關注。
 

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