LUXCEL讓您輕松研究細(xì)胞代謝

瀏覽次數(shù)：1869　發(fā)布日期：2013-8-29　來源：本站　僅供參考，謝絕轉(zhuǎn)載，否則責(zé)任自負(fù)

簡單方法，研究細(xì)胞代謝!

試劑廠家LUXCEL提供獨有的時間分辨熒光探針技術(shù)，令研究者可在 BMG高端TRF熒光酶標(biāo)儀上用細(xì)胞或分離的線粒體進(jìn)行簡單的，高通量的和實時的胞外氧消秏量(ecOCR)，胞內(nèi)氧消秏量(icOCR)和胞外酸化率(ECA)等代謝指標(biāo)檢測。

綜合不同LUXCEL試劑，研究者可在同一樣本中進(jìn)行多個細(xì)胞代謝，線粒體功能與毒性指標(biāo)檢測(e.g. ORC，ECA和ATP) 。

·MitoXpress®Xtra-檢測胞外氧消秏

·MitoXpress®Intra-檢測胞內(nèi)氧消秏

·pH-Xtra^TM-檢測胞外酸化率

相關(guān)學(xué)術(shù)文章：

The Enzymatic Activity of Apoptosis Inducing Factor Supports Energy Metabolism Benefitting the Growth and Invasiveness of Advanced Prostate Cancer Cells Lewis EM, Wilkinson AS, Jackson JS, Mehra R, Varambally S, Chinnaiyan AM, Wilkinson JC., J Biol Chem. (2012 Nov) .

Galloflavin, a new lactate dehydrogenase inhibitor, induces the death of human breast cancer cells with different glycolytic attitude by affecting distinct signaling pathways Farabegoli F, Vettraino M, Manerba M, Fiume L, Roberti M, Di Stefano G., Eur J Pharm Sci. (2012 Nov); 47(4):729-38

Prediction of liver injury induced by chemicals in human with a multiparametric assay on isolated mouse liver mitochondria Porceddu M, Buron N, Roussel C, Labbe G, Fromenty B, Borgne-Sanchez A. Toxicol Sci. (2012 Oct);129(2):332-45

Overexpression of Pyruvate Dehydrogenase Kinase 1 and Lactate Dehydrogenase A in Nerve Cells Confers Resistance to Amyloid β and Other Toxins by Decreasing Mitochondrial Respiration and Reactive Oxygen Species Production Newington JT, Rappon T, Albers S, Wong DY, Rylett RJ, Cumming RC., J Biol. (2012 Oct); 287(44):37245-58

Lipolytic products activate peroxisome proliferator-activated receptor (PPAR) α and δ in brown adipocytes to match fatty acid oxidation with supply

Mottillo EP, Bloch AE, Leff T, Granneman JG. J Biol Chem. (2012 Jul); 287(30):25038-48

Geranylgeraniol oxidase activity involved in oxidative formation of geranylgeranoic acid in human hepatoma cells

Mitake M, Shidoji Y., Biomed Res. (2012 Feb);33(1):15-24

Nuclear Expression of a Mitochondrial DNA Gene: Mitochondrial Targeting of Allotopically Expressed Mutant ATP6 in Transgenic Mice

Dunn, Carl A. Pinker, J Biomed Biotechnol. (2012)

Modular microfluidic system as a model of cystic fibrosis airways

Skolimowski M, Nielsen MW, Abeille F, Skafte-Pedersen P, Sabourin D, Fercher A, Papkovsky D, Molin S, Taboryski R, Sternberg C, Dufva M, Geschke O, Emnéus J., Biomicrofluidics, (2012), 6, 034109

In vitro approach to predict post-translational phosphorylation response to mixtures

Jonathan Boyd, Julie A. Vrana, Holly N. Williams, Tox (2012)

A high-throughput dual parameter assay for assessing drug-induced mitochondrial dysfunction provides additional predictivity over two established mitochondrial …

J Hynes, S Nadanaciva, R Swiss, C Carey, S Kirwan… – Toxicology in Vitro, 2012

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標(biāo)簽：細(xì)胞代謝線粒體功能胞外氧消耗量時間分辨熒光探針技術(shù)

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LUXCEL讓您輕松研究細(xì)胞代謝