306 次血管內皮-間充質串擾通過 Notch 信號驅動人成骨細胞的成骨分化 2025-6-4
Endothelial-mesenchymal crosstalk drives osteogenic differentiation of human osteoblasts through Notch signalingKeywords: Co-culture; Endothelial cells; Notch signaling; Osteoblast
240 次TRPV4 抑制劑和機械負荷對減輕炎癥的協同作用 2025-6-3
Synergetic role of TRPV4 inhibitor and mechanical loading on reducing inflammationKeywords: anti-inflammatory phenotype; inhibition, mechanical loading; macrophage polarization; mi
295 次I 類 PI3Ks 激活小梁網細胞中拉伸誘導的自噬 2025-5-27
Class I PI3Ks activate stretch-induced autophagy in trabecular meshwork cellsKeywords: Autophagy; Glaucoma; Mechanical stress; PI3K; Primary cilia; Trabecular meshwork.眼壓升高(IO
335 次c-REL串擾TXNIP-p38與非經典NF-κB通路協調紊亂血流區動脈粥樣硬化 2025-5-20
Endothelial c-REL orchestrates atherosclerosis at regions of disturbed flow through crosstalk with TXNIP-p38 and non-canonical NF-κB pathwaysKWS:c-REL, Shear stress, Endothe
247 次動脈粥樣硬化中血流誘導的內皮細胞重編程 2025-5-19
Flow-induced reprogramming of endothelial cells in atherosclerosisSubject terms: Cell biology, Systems biology動脈粥樣硬化是一種主要影響動脈的多因素慢性炎癥性疾病。內皮細胞功能障礙
378 次CUT&Tag 技術原理及應用介紹 2025-5-13
在表觀遺傳學的研究領域中,蛋白質與DNA的相互作用一直是探索基因表達調控奧秘的關鍵所在。而CUT&Tag(Cleavage Under Targets & Tagmentation)技術,即靶向剪切及轉座酶技術,作為一種
320 次E2F1誘導IL-6炎癥循環介導癌癥免疫,預測T細胞表型轉換和治療反應 2025-5-13
E2F1-induced autocrine IL-6 inflammatory loop mediates cancer-immune crosstalk that predicts T cell phenotype switching and therapeutic responsivenessKeywords: CD4 +/CD8 + T cells;
304 次IL-33 經 OX40L 促進人肥大細胞誘導 CD4+ T 細胞產生 IL-9 2025-5-12
IL-33-primed human mast cells drive IL-9 production by CD4+ effector T cells in an OX40L-dependent mannerKeywords: IL-33; IL-9; OX40L; Th cell; mast cell.2 型免疫反應是針對皮膚和粘
337 次運動減輕血流再循環激活代謝轉能器 SCD1 催化血管保護性代謝物 2025-5-7
Exercise mitigates flow recirculation and activates metabolic transducer SCD1 to catalyze vascular protective metabolitesKS:Exercise;flow recirculation;SCD1作為對周期性心臟收縮的